• Recurring sores in the genital region.
• Eye conditions could be examined by an eye specialist for identifying symptoms of ocular inflammation.
• An array of rash or pimple-like sore formations could develop due to Behçet’s disease.
• A pathergy test would be conducted involving the insertion of a sterile needle inside the skin and then examining the site 2 days anon. In case the outcome of the pathergy test are affirmative then a tiny reddish lump develops underneath the skin’s surface on the site of jab insertion indicative of overreaction of the immune system to the small wound.

Treatment and Medications

With absence of any cure in case of Behçet’s disease, certain drugs would be medically advised for controlling transitory painful and inflammation flare-ups. Systemic drugs would be advised for controlling Behçet’s disease symptoms all through the body along with transitory flare-up controlling medicines.

• Medications containing corticosteroid drug (anti-inflammatory and anesthetizing) that could be topically applied to the skin like cream, gel and ointment for reducing inflammation and pain.
• Specially intended for oral rinsing – corticosteroid-comprising mouthwashes for allaying discomforting sensation of oral sores.
• Corticosteroid or other inflammation-fighting eye drops could assuage pain and reddishness in the eyes in case inflammation is mild-ranging.

Systemic Treatments

In moderate to severe-ranging Behçet’s disease, the following prescriptions would be advised.

• Corticosteroids like prednisone coalesced with other medicines could allay inflammation arising due to Behçet’s disease. As the disease has been observed to relapse when solely corticosteroids are prescribed, hence they are mostly advised alongside other medicines for suppressing immune system activity (immunosuppressive medications). Associated side effects of corticosteroids comprise of weight increase, persistently lasting heartburn, hypertension and osteoporosis.
• Immunosuppressive medications suppress the immune system that reacts excessively in Behçet’s disease. When the immune system is prevented from assaulting normal tissues in the body, immunosuppressive medicines lower inflammation that the immune system causes. Immunosuppressive medication that could don a task in curbing Behçet’s disease comprises of azathioprine – Azasan, Imuran, cyclosporine – Sandimmune and cyclophosphamide – Cytoxan. As these could repress the action of one’s immune system, they could raise the chances of developing infection. Other likely side effects comprise of liver, kidney ailments, depleted blood count and hypertension.
• Immune system regulating medicines like Interferon alfa or Intron A for controlling inflammation, skin sores, joint aches and ocular inflammation. Side effects comprise of flu similar symptoms like muscular aches and weariness. Just lately, small-scaled studies have indicated that medicines which function by blocking TNF or tumor necrosis factor for instance infliximab and etanercept could be beneficial in treatment of Behçet’s disease. Colchicine, methotrexate could also be useful in treatment of Behçet’s disease.